The Buck Institute is the nation’s first and foremost non-profit research organization devoted to Geroscience, which is focused on the connection between normal aging and chronic disease. Our creative, interdisciplinary approach involves collaborations between laboratories studying:

  • The mechanisms of aging
  • Age-related diseases
  • Stem cell technologies and regenerative medicine

Buck scientists strive to discover new ways of detecting, preventing, delaying and treating age-related conditions such as Alzheimer’s and Parkinson’s, cancer, cardiovascular disease, macular degeneration, diabetes and stroke.

Recent Publications:
  • "Fluorescence measurement of mitochondrial membrane potential changes in cultured cells." Methods Mol. Biol. 810 119-33
  • "Plasma Membrane Potential Oscillations in Insulin Secreting Ins-1 832/13 Cells do not Require Glycolysis and are not Initiated by Fluctuations in Mitochondrial Bioenergetics." The Journal of biological chemistry 287:19 15706-17
  • "Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria." The Journal of physiology
More publications from the Nicholls Lab...
Core Technologies:
Bioinfomatics >
Chemistry & Spectrometry >
Genomics >
Morphology & Imaging >
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