Hillblom Center

The Larry L. Hillblom Center for Integrative Studies of Aging brings together researchers with overlapping interests in the basic biology of aging. It is a highly efficient and collaborative space that helps speed progress towards new discoveries.

The new wet laboratory and laboratory support areas encourage cross-disciplinary science and the development of innovative research. There are currently four research groups occupying this state-of-the-art facility each lead by Buck faculty. Judith Campisi, PhD, is internationally known for her research on the relationship between cancer and aging. Simon Melov, PhD, is an expert in genomics, metabolism and aging in model organisms and humans. Pankaj Kapahi, PhD, studies the relationship between nutrition and aging in model organisms and Gordon J. Lithgow, PhD, is an expert in stress and aging. The four laboratories have extensive collaborations as function of the workspace, and have become very integrated with a free flow of information and reagents throughout the Center. A number of prominent discoveries have been published from the Center.

The Buck Institute for Research on Aging was granted $2,000,000 from the Larry L. Hillblom Foundation in 2007 to create the Larry L. Hillblom Center for Integrative Studies of Aging. The objective of the grant was to provide 11,700 square feet of new laboratory space to house up to five research programs.

Ribbon cutting for new Center, August 2, 2007; Peter Donnici, President Larry L. Hillblom Foundation;  E. Lewis Reid, Buck Trustee; Dale Bredesen, MD, Buck Institute CEO The Kapahi lab is located in the Hillblom Center

News from the Hillblom Center

Physical Activity Needed In Order To Reap Benefits Of Dietary Restriction

Need an Excuse to Book a Massage? Research Shows it Reduces Inflammation and Promotes Growth of New Mitochondria Following Strenuous Exercise

Researchers Flip the Switch Between Aging and Development in C. elegans

A New Role for Endocannabinoid Signaling in Dietary Restriction and Lifespan Extension

Common Laboratory Dye is a Wonder Drug -- for Worms

A New Role for Insulin in Cell Survival, Cell Metabolism and Stress Response

Fruit Flies Provide New Clues on How Organisms Make Dietary Choices

"Anti-Atkins" Low Protein Diet Extends Lifespan in Flies

DNA Damaged Cells Communicate with Neighbors to Let them Know They’re in Trouble

Buck Scientists Identify a Key Protein That May Explain the Anti-Aging and Anti-Cancer Benefits of Dietary Restriction

Escape Cancer, But Age Sooner?

Buck Study Uses Biomarkers of Aging to Predict Chronological and Physiological Age

Buck Institute Study Shows Mixed Results for Life-Extending Properties of Antioxidants

Drug Commonly Used to Treat Bi-Polar Disorder Dramatically Increases Lifespan in Nematode Worms


Publications from the Hillblom Center


Bat-Erdene Myagmar, James M Flynn... Paul C Simpson "Adrenergic Receptors in Individual Ventricular Myocytes: The Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent." Circ. Res.
Christopher D Wiley, James M Flynn... Judith Campisi "Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence." Aging Cell
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